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  Domain Name: C1_1
Phorbol esters/diacylglycerol binding domain (C1 domain). This domain is also known as the Protein kinase C conserved region 1 (C1) domain.
No pairwise interactions found for the domain C1_1

Total Mutations Found: 20
Total Disease Mutations Found: 18
This domain occurred 58 times on human genes (109 proteins).



  CARDIOFACIOCUTANEOUS SYNDROME 1
  DUANE RETRACTION SYNDROME 2
  HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 7
  LEOPARD SYNDROME 3, INCLUDED
  NOONAN SYNDROME 7
  SPINOCEREBELLAR ATAXIA 14


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for C1_1







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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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