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  Domain Name: CA
Cadherin repeats. Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.
No pairwise interactions found for the domain CA

Total Mutations Found: 328
Total Disease Mutations Found: 51
This domain occurred 114 times on human genes (191 proteins).



  ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA, FAMILIAL, 10
  DEAFNESS, AUTOSOMAL RECESSIVE 12
  DEAFNESS, AUTOSOMAL RECESSIVE 23
  DEAFNESS, AUTOSOMAL RECESSIVE, 12 (DFNB12)
  ECTODERMAL DYSPLASIA, ECTRODACTYLY, AND MACULAR DYSTROPHY
  EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 9
  GASTRIC CANCER, HEREDITARY DIFFUSE
  HYPOTRICHOSIS 6
  HYPOTRICHOSIS, CONGENITAL, WITH JUVENILE MACULAR DYSTROPHY
  MENTAL RETARDATION, AUTOSOMAL DOMINANT 3
  PALMOPLANTAR KERATODERMA I, STRIATE
  USHER SYNDROME 1D (USH1D)
  USHER SYNDROME, TYPE ID
  USHER SYNDROME, TYPE IF
  VAN MALDERGEM SYNDROME 1
  VAN MALDERGEM SYNDROME 2


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Range on the Protein:  

   Protein ID            Protein Position