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  Domain Name: CCP
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system. SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.
No pairwise interactions are available for this conserved domain.

Total Mutations Found: 150
Total Disease Mutations Found: 32
This domain occurred 49 times on human genes (110 proteins).



  BASAL LAMINAR DRUSEN
  BASAL LAMINAR DRUSEN, INCLUDED
  COMPLEMENT FACTOR H DEFICIENCY
  COMPLEMENT FACTOR H DEFICIENCY (CFHD)
  CROMER BLOOD GROUP SYSTEM, INAB PHENOTYPE
  FACTOR XIII, B SUBUNIT, DEFICIENCY OF
  HEMOLYTIC UREMIC SYNDROME ATYPICAL 1 (AHUS1)
  HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1
  HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 2
  MACULAR DEGENERATION, AGE-RELATED, 4, SUSCEPTIBILITY TO
  ROLANDIC EPILEPSY, MENTAL RETARDATION, AND SPEECH DYSPRAXIA, X-LINKED
  VARIANT OF UNKNOWN SIGNIFICANCE
  VENOUS THROMBOSIS, SUSCEPTIBILITY TO


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


Feature Name:Total Found:
receptor-ligand interacti










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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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