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  Domain Name: CCP
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR). The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.
No pairwise interactions found for the domain CCP

Total Mutations Found: 164
Total Disease Mutations Found: 33
This domain occurred 53 times on human genes (127 proteins).



  BASAL LAMINAR DRUSEN
  BASAL LAMINAR DRUSEN, INCLUDED
  C2 DEFICIENCY, TYPE II
  COMPLEMENT FACTOR H DEFICIENCY
  COMPLEMENT FACTOR H DEFICIENCY (CFHD)
  CROMER BLOOD GROUP SYSTEM, INAB PHENOTYPE
  FACTOR XIII, B SUBUNIT, DEFICIENCY OF
  HEMOLYTIC UREMIC SYNDROME ATYPICAL 1 (AHUS1)
  HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1
  HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 2
  MACULAR DEGENERATION, AGE-RELATED, 4, SUSCEPTIBILITY TO
  RECLASSIFIED - VARIANT OF UNKNOWN SIGNIFICANCE
  ROLANDIC EPILEPSY, MENTAL RETARDATION, AND SPEECH DYSPRAXIA, X-LINKED
  VARIANT OF UNKNOWN SIGNIFICANCE
  VENOUS THROMBOSIS, SUSCEPTIBILITY TO


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for CCP








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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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