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  Domain Name: CNX
Connexin homologues. Connexin channels participate in the regulation of signaling between developing and differentiated cell types.
No pairwise interactions found for the domain CNX

Total Mutations Found: 21
Total Disease Mutations Found: 19
This domain occurred 20 times on human genes (36 proteins).



  ATRIAL FIBRILLATION, FAMILIAL, 11
  CATARACT 1 WITH MICROCORNEA
  CATARACT 1, MULTIPLE TYPES
  CATARACT 1, ZONULAR PULVERULENT
  CATARACT 14, ZONULAR PULVERULENT
  CHARCOT-MARIE-TOOTH DISEASE, X-LINKED DOMINANT, 1
  DEAFNESS, AUTOSOMAL DOMINANT 3A
  DEAFNESS, AUTOSOMAL RECESSIVE 1A
  DEAFNESS, AUTOSOMAL RECESSIVE 1A, INCLUDED
  HYSTRIX-LIKE ICHTHYOSIS WITH DEAFNESS, INCLUDED
  KERATITIS-ICHTHYOSIS-DEAFNESS SYNDROME, AUTOSOMAL DOMINANT
  KERATODERMA, PALMOPLANTAR, WITH DEAFNESS
  KNUCKLE PADS, LEUKONYCHIA, AND SENSORINEURAL DEAFNESS
  LYMPHEDEMA, HEREDITARY, IC
  VOHWINKEL SYNDROME


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for CNX





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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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