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  Domain Name: CUB
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.

Total Mutations Found: 67
Total Disease Mutations Found: 7
This domain occurred 48 times on human genes (106 proteins).



  3MC SYNDROME 1
  ATRIAL SEPTAL DEFECT 6
  CARPENTER SYNDROME 2 (CRPT2)
  MASP2 DEFICIENCY
  MEGALOBLASTIC ANEMIA 1, FINNISH TYPE
  NANOPHTHALMOS 2


Tips:
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 The histograms below the weblogo indicate mutations found on the domain. Red is for disease (OMIM) and blue is for SNPs.

 Functional Features are displayed as orange boxes under the histograms. You can choose which features are displayed in the box below.



Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for CUB











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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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