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  Domain Name: Cation_efflux
Cation efflux family. Members of this family are integral membrane proteins, that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells.
No pairwise interactions found for the domain Cation_efflux

Total Mutations Found: 17
Total Disease Mutations Found: 4
This domain occurred 10 times on human genes (19 proteins).



  DIABETES MELLITUS, NONINSULIN-DEPENDENT, SUSCEPTIBILITY TO
  HYPERMANGANESEMIA WITH DYSTONIA, POLYCYTHEMIA, AND CIRRHOSIS
  ZINC DEFICIENCY, TRANSIENT NEONATAL


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for Cation_efflux
























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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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