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  Domain Name: CypX
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]
No pairwise interactions found for the domain CypX

Total Mutations Found: 369
Total Disease Mutations Found: 116
This domain occurred 56 times on human genes (97 proteins).



  17,20-@LYASE DEFICIENCY, ISOLATED
  17-@ALPHA-HYDROXYLASE/17,20-LYASE DEFICIENCY, COMBINED COMPLETE
  17-@ALPHA-HYDROXYLASE/17,20-LYASE DEFICIENCY, COMBINED PARTIAL
  ADENOMA, CORTISOL-PRODUCING, INCLUD
  ADRENAL HYPERPLASIA, CONGENITAL, DUE TO 21-HYDROXYLASE DEFICIENCY
  ADRENAL HYPERPLASIA, CONGENITAL, DUE TO 21-HYDROXYLASE DEFICIENCY,
  ADRENAL HYPERPLASIA, CONGENITAL, DUE TO STEROID 11-BETA-HYDROXYLASE
  ADRENAL INSUFFICIENCY, CONGENITAL, WITH 46,XY SEX REVERSAL, PARTIAL
  AROMATASE DEFICIENCY
  BIETTI CRYSTALLINE CORNEORETINAL DYSTROPHY
  BILE ACID SYNTHESIS DEFECT, CONGENITAL, 3
  BREAST CANCER, SUSCEPTIBILITY TO, INCLUDED
  CEREBROTENDINOUS XANTHOMATOSIS
  CLASSIC TYPE
  CYP2A6*11
  DEBRISOQUINE, POOR METABOLISM OF
  DEBRISOQUINE, ULTRARAPID METABOLISM OF
  DEFICIENCY
  EFAVIRENZ CENTRAL NERVOUS SYSTEM TOXICITY, SUSCEPTIBILITY TO, INCLUDED
  EFAVIRENZ, POOR METABOLISM OF
  GHOSAL HEMATODIAPHYSEAL SYNDROME
  GLIPIZIDE POOR M
  HYPERCALCEMIA, INFANTILE
  ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 5
  MEPHENYTOIN, POOR METABOLISM OF
  NONCLASSIC TYPE
  OR COMPLETE
  PHENYTOIN POOR METABOLIZER, INCLUDED;;
  PROGUANIL, POOR METABOLISM OF, INCLUDED
  RADIOHUMERAL FUSIONS WITH OTHER SKELETAL AND CRANIOFACIAL ANOMALIES
  SALT-WASTING TYPE
  SPASTIC PARAPLEGIA 56, AUTOSOMAL RECESSIVE
  SPASTIC PARAPLEGIA 5A, AUTOSOMAL RECESSIVE
  SPASTIC PARAPLEGIA 5A, AUTOSOMAL RECESSIVE, INCLUDED
  TEGAFUR, POOR METABOLISM OF
  TOLBUTAMIDE POOR METABOLIZER
  VITAMIN D HYDROXYLATION-DEFICIENT RICKETS, TYPE 1A
  VITAMIN D HYDROXYLATION-DEFICIENT RICKETS, TYPE 1B
  WARFARIN SENSITIVITY
  WARFARIN SENSITIVITY, INCLUDED;;


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for CypX



















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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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