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  Domain Name: DCX
Ubiquitin-like domain of DCX. DCX The ubiquitin-like DCX domain is present in tandem within the N-terminal half of the doublecortin protein. Doublecortin is expressed in migrating neurons. Mutations in the gene encoding doublecortin cause lissencephaly in males and 'double-cortex syndrome' in females.
No pairwise interactions are available for this conserved domain.

Total Mutations Found: 42
Total Disease Mutations Found: 7
This domain occurred 8 times on human genes (18 proteins).



  LISSENCEPHALY, X-LINKED, 1
  OCCULT MACULAR DYSTROPHY (OCMD)
  SUBCORTICAL LAMINAR HETEROTOPIA, X-LINKED, INCLUDED


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


Feature Name:Total Found:
XLIS mutations
SBH mutations










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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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