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  Domain Name: DCX
Domain in the Doublecortin (DCX) gene product. Tandemly-repeated domain in doublin, the Doublecortin gene product. Proposed to bind tubulin. Doublecortin (DCX) is mutated in human X-linked neuronal migration defects.
No pairwise interactions found for the domain DCX

Total Mutations Found: 49
Total Disease Mutations Found: 8
This domain occurred 9 times on human genes (20 proteins).



  LISSENCEPHALY, X-LINKED, 1
  OCCULT MACULAR DYSTROPHY (OCMD)
  OCCULT MACULAR DYSTROPHY, SUSCEPTIBILITY TO
  SUBCORTICAL LAMINAR HETEROTOPIA, X-LINKED, INCLUDED


Tips:
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 The histograms below the weblogo indicate mutations found on the domain. Red is for disease (OMIM) and blue is for SNPs.

 Functional Features are displayed as orange boxes under the histograms. You can choose which features are displayed in the box below.



Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for DCX







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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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