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  Domain Name: DEATH
DEATH domain, found in proteins involved in cell death (apoptosis). Alpha-helical domain present in a variety of proteins with apoptotic functions. Some (but not all) of these domains form homotypic and heterotypic dimers.
No pairwise interactions found for the domain DEATH

Total Mutations Found: 12
Total Disease Mutations Found: 4
This domain occurred 27 times on human genes (78 proteins).



  AND CARDIOVASCULAR MALFORMATIONS
  ASTHMA SUSCEPTIBILITY 5
  INFECTIONS, RECURRENT, ASSOCIATED WITH ENCEPHALOPATHY, HEPATIC DYSFUNCTION,
  MENTAL RETARDATION, AUTOSOMAL RECESSIVE 34
  MYD88 DEFICIENCY


Tips:
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 The histograms below the weblogo indicate mutations found on the domain. Red is for disease (OMIM) and blue is for SNPs.

 Functional Features are displayed as orange boxes under the histograms. You can choose which features are displayed in the box below.



Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for DEATH









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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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