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  Domain Name: DYNc
Dynamin, GTPase. Large GTPases that mediate vesicle trafficking. Dynamin participates in the endocytic uptake of receptors, associated ligands, and plasma membrane following an exocytic event.
No pairwise interactions found for the domain DYNc

Total Mutations Found: 65
Total Disease Mutations Found: 62
This domain occurred 7 times on human genes (38 proteins).



  ATAXIA, AND NEUROPATHY
  ATAXIA, AND NEUROPATHY, INCLUDED
  CHARCOT-MARIE-TOOTH DISEASE 2M (CMT2M)
  ENCEPHALOPATHY, LETHAL, DUE TO DEFECTIVE MITOCHONDRIAL AND PEROXISOMAL FISSION (EMPF)
  LETHAL CONGENITAL CONTRACTURE SYNDROME 5 (LCCS5)
  MYOPATHY, CENTRONUCLEAR, 1 (CNM1)
  OPTIC ATROPHY 1
  OPTIC ATROPHY WITH OR WITHOUT DEAFNESS, OPHTHALMOPLEGIA, MYOPATHY,


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for DYNc











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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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