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  Domain Name: GCV_T_C
Glycine cleavage T-protein C-terminal barrel domain. This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyzes the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase.

Total Mutations Found: 5
Total Disease Mutations Found: 4
This domain occurred 5 times on human genes (12 proteins).



  GLYCINE ENCEPHALOPATHY
  MULTIPLE MITOCHONDRIAL DYSFUNCTIONS SYNDROME 3 (1 FAMILY)


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for GCV_T_C











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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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