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  Domain Name: Gasdermin
Gasdermin family. The precise function of this protein is unknown. A deletion/insertion mutation is associated with an autosomal dominant non-syndromic hearing impairment form. In addition, this protein has also been found to contribute to acquired etoposide resistance in melanoma cells. This family also includes the gasdermin protein
No pairwise interactions found for the domain Gasdermin

Total Mutations Found: 42
Total Disease Mutations Found: 5
This domain occurred 6 times on human genes (10 proteins).



  DEAFNESS, AUTOSOMAL RECESSIVE 59
  DEAFNESS, AUTOSOMAL RECESSIVE, 59 (DFNB59)


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for Gasdermin




















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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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