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  Domain Name: Helicase_C
Helicase conserved C-terminal domain. The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.
No pairwise interactions found for the domain Helicase_C

Total Mutations Found: 40
Total Disease Mutations Found: 12
This domain occurred 90 times on human genes (151 proteins).



  AUTISM, SUSCEPTIBILITY TO, 18
  MENTAL RETARDATION, AUTOSOMAL DOMINANT 16
  NICOLAIDES-BARAITSER SYNDROME
  PLEUROPULMONARY BLASTOMA
  RHABDOID TUMOR PREDISPOSITION SYNDROME 2
  SCHIMKE IMMUNOOSSEOUS DYSPLASIA


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for Helicase_C









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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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