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  Domain Name: Hist_deacetyl
Histone deacetylase domain. Histones can be reversibly acetylated on several lysine residues. Regulation of transcription is caused in part by this mechanism. Histone deacetylases catalyze the removal of the acetyl group. Histone deacetylases are related to other proteins.
No pairwise interactions found for the domain Hist_deacetyl

Total Mutations Found: 10
Total Disease Mutations Found: 8
This domain occurred 11 times on human genes (28 proteins).



  CORNELIA DE LANGE SYNDROME 5


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for Hist_deacetyl


































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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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