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  Domain Name: IG_FLMN
Filamin-type immunoglobulin domains. These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).
No pairwise interactions found for the domain IG_FLMN

Total Mutations Found: 76
Total Disease Mutations Found: 30
This domain occurred 9 times on human genes (20 proteins).



  ATELOSTEOGENESIS, TYPE III
  CARDIAC VALVULAR DYSPLASIA, X-LINKED
  FG SYNDROME 2
  FRONTOMETAPHYSEAL DYSPLASIA
  HETEROTOPIA, PERIVENTRICULAR NODULAR, X-LINKED DOMINANT
  LARSEN SYNDROME
  MELNICK-NEEDLES SYNDROME
  MYOPATHY, MYOFIBRILLAR, 5
  OTOPALATODIGITAL SPECTRUM DISORDER
  SPONDYLOCARPOTARSAL SYNOSTOSIS SYNDROME


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for IG_FLMN










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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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