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  Domain Name: Inhibitor_I29
Cathepsin propeptide inhibitor domain (I29). This domain is found at the N-terminus of some C1 peptidases such as Cathepsin L where it acts as a propeptide. There are also a number of proteins that are composed solely of multiple copies of this domain such as the peptidase inhibitor salarin. This family is classified as I29 by MEROPS.
No pairwise interactions found for the domain Inhibitor_I29

Total Mutations Found: 3
Total Disease Mutations Found: 3
This domain occurred 7 times on human genes (16 proteins).



  CEROID LIPOFUSCINOSIS, NEURONAL, 13
  PYCNODYSOSTOSIS


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for Inhibitor_I29








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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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