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  Domain Name: Insulin
Insulin/IGF/Relaxin family. Superfamily includes insulins; relaxins; insulin-like growth factor; and bombyxin. All are secreted regulatory hormones. Disulfide rich, all-alpha fold. Alignment includes B chain, linker (which is processed out of the final product), and A chain.
No pairwise interactions found for the domain Insulin

Total Mutations Found: 14
Total Disease Mutations Found: 13
This domain occurred 7 times on human genes (16 proteins).



  CRYPTORCHIDISM
  DIABETES MELLITUS, INSULIN-DEPENDENT, 2
  DIABETES MELLITUS, PERMANENT NEONATAL
  HYPERPROINSULINEMIA, FAMILIAL
  MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 10
  PROINSULIN KYOTO


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for Insulin









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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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