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  Domain Name: K_tetra
K+ channel tetramerisation domain. The N-terminal, cytoplasmic tetramerisation domain (T1) of voltage-gated K+ channels encodes molecular determinants for subfamily-specific assembly of alpha-subunits into functional tetrameric channels. It is distantly related to the BTB/POZ domain pfam00651.

Total Mutations Found: 13
Total Disease Mutations Found: 7
This domain occurred 41 times on human genes (64 proteins).



  EPILEPSY, PROGRESSIVE MYOCLONIC 3, WITHOUT INTRACELLULAR INCLUSIONS
  RETINAL CONE DYSTROPHY 3B


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for K_tetra








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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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