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  Domain Name: LU
Ly-6 antigen / uPA receptor -like domain. Three-fold repeated domain in urokinase-type plasminogen activator receptor; occurs singly in other GPI-linked cell-surface glycoproteins (Ly-6 family, CD59, thymocyte B cell antigen, Sgp-2). Topology of these domains is similar to that of snake venom neurotoxins.
No pairwise interactions found for the domain LU

Total Mutations Found: 8
Total Disease Mutations Found: 1
This domain occurred 8 times on human genes (20 proteins).



  HEMOLYTIC ANEMIA, CD59-MEDIATED, WITH IMMUNE-MEDIATED POLYNEUROPATHY


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for LU







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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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