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  Domain Name: Lig_chan-Glu_bd
Ligated ion channel L-glutamate- and glycine-binding site. This region, sometimes called the S1 domain, is the luminal domain just upstream of the first, M1, transmembrane region of transmembrane ion-channel proteins, and it binds L-glutamate and glycine. It is found in association with Lig_chan, pfam00060.
No pairwise interactions found for the domain Lig_chan-Glu_bd

Total Mutations Found: 2
Total Disease Mutations Found: 1
This domain occurred 18 times on human genes (55 proteins).



  MENTAL RETARDATION, AUTOSOMAL DOMINANT 6


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for Lig_chan-Glu_bd







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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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