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  Domain Name: Myelin-PO_C
Myelin-PO cytoplasmic C-term p65 binding region. Myelin protein zero is the major myelin protein in the peripheral central nervous system and is essential for normal myelination. The family is a single-pass transmembrane molecule containing one Ig-like loop in the extracellular domain and this highly basic 69 residue C-terminal cytoplasmic domain which is the region that interacts with protein p65.
No pairwise interactions found for the domain Myelin-PO_C

Total Mutations Found: 2
Total Disease Mutations Found: 2
This domain occurred 1 times on human genes (2 proteins).



  CHARCOT-MARIE-TOOTH DISEASE, TYPE 1B
  NEUROPATHY, CONGENITAL HYPOMYELINATING, AUTOSOMAL DOMINANT


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for Myelin-PO_C






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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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