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  Domain Name: PI3K_1B_p101
Phosphoinositide 3-kinase gamma adapter protein p101 subunit. Class I PI3Ks are dual-specific lipid and protein kinases involved in numerous intracellular signaling pathways. Class IB PI3K, p110gamma, is mainly activated by seven-transmembrane G-protein-coupled receptors (GPCRs), through its regulatory subunit p101 and G-protein beta-gamma subunits.
No pairwise interactions found for the domain PI3K_1B_p101

Total Mutations Found: 1
Total Disease Mutations Found: 1
This domain occurred 2 times on human genes (9 proteins).



  ATAXIA-OCULOMOTOR APRAXIA 3 (AOA3)


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for PI3K_1B_p101






























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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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