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  Domain Name: PLAT_repeat
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins.
No pairwise interactions are available for this conserved domain.

Total Mutations Found: 39
Total Disease Mutations Found: 24
This domain occurred 14 times on human genes (27 proteins).



  ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 2
  ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 2 (ARCI2)
  ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 3
  ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 3 (ARCI3)
  RECLASSIFIED - VARIANT OF UNKNOWN SIGNIFICANCE


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for PLAT_repeat









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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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