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  Domain Name: PTPc_DSPc
Protein tyrosine phosphatase, catalytic domain, undefined specificity. Protein tyrosine phosphatases. Homologues detected by this profile and not by those of "PTPc" or "DSPc" are predicted to be protein phosphatases with a similar fold to DSPs and PTPs, yet with unpredicted specificities.
No pairwise interactions found for the domain PTPc_DSPc

Total Mutations Found: 50
Total Disease Mutations Found: 31
This domain occurred 57 times on human genes (127 proteins).



  BANNAYAN-RILEY-RUVALCABA SYNDROME
  BANNAYAN-RILEY-RUVALCABA SYNDROME, INCLUDED;;
  CHARCOT-MARIE-TOOTH DISEASE, TYPE 4B1
  COWDEN DISEASE 1
  LEOPARD SYNDROME
  LHERMITTE-DUCLOS DISEASE
  MACROCEPHALY/AUTISM SYNDROME
  MACROCEPHALY/AUTISM SYNDROME, INCLUDED
  METACHONDROMATOSIS
  MYOTUBULAR MYOPATHY, X-LINKED
  NOONAN SYNDROME
  NOONAN SYNDROME 1
  PTEN HAMARTOMA TUMOR SYNDROME
  SQUAMOUS CELL CARCINOMA, HEAD AND NECK, SOMATIC
  VARIANT OF UNKNOWN SIGNIFICANCE


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for PTPc_DSPc














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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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