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  Domain Name: RFX_DNA_binding
RFX DNA-binding domain. RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer.
No pairwise interactions found for the domain RFX_DNA_binding

Total Mutations Found: 1
Total Disease Mutations Found: 1
This domain occurred 8 times on human genes (11 proteins).



  AND GALLBLADDER APLASIA OR HYPOPLASIA
  DIABETES, NEONATAL, WITH PANCREATIC HYPOPLASIA, INTESTINAL ATRESIA,


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for RFX_DNA_binding







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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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