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  Domain Name: RNA_pol_Rpb1_1
RNA polymerase Rpb1, domain 1. RNA polymerases catalyze the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). This domain, domain 1, represents the clamp domain, which a mobile domain involved in positioning the DNA, maintenance of the transcription bubble and positioning of the nascent RNA strand.
No pairwise interactions found for the domain RNA_pol_Rpb1_1

Total Mutations Found: 4
Total Disease Mutations Found: 1
This domain occurred 3 times on human genes (5 proteins).



  LEUKODYSTROPHY, HYPOMYELINATING, 7, WITH OLIGODONTIA


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Range on the Protein:  

   Protein ID            Protein Position

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No Conserved Features/Sites Found for RNA_pol_Rpb1_1
















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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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