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  Domain Name: RYDR_ITPR
RIH domain. The RIH (RyR and IP3R Homology) domain is an extracellular domain from two types of calcium channels. This region is found in the ryanodine receptor and the inositol-1,4,5- trisphosphate receptor. This domain may form a binding site for IP3.

Total Mutations Found: 20
Total Disease Mutations Found: 10
This domain occurred 6 times on human genes (16 proteins).



  CENTRAL CORE DISEASE, INCLUDED
  MALIGNANT HYPERTHERMIA, SUSCEPTIBILITY TO, 1
  SPINOCEREBELLAR ATAXIA 29
  VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for RYDR_ITPR











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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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