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  Domain Name: SAM_1
SAM domain (Sterile alpha motif). It has been suggested that SAM is an evolutionarily conserved protein binding domain that is involved in the regulation of numerous developmental processes in diverse eukaryotes. The SAM domain can potentially function as a protein interaction module through its ability to homo- and heterooligomerise with other SAM domains.
No pairwise interactions found for the domain SAM_1

Total Mutations Found: 15
Total Disease Mutations Found: 4
This domain occurred 75 times on human genes (118 proteins).



  CATARACT 6, POSTERIOR POLAR
  MICROCEPHALY 11, PRIMARY, AUTOSOMAL RECESSIVE (1 FAMILY)
  RENAL DYSPLASIA, CYSTIC, SUSCEPTIBILITY TO


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for SAM_1






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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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