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  Domain Name: SCF
Stem cell factor. Stem cell factor (SCF) is a homodimer involved in hematopoiesis. SCF binds to and activates the SCF receptor (SCFR), a receptor tyrosine kinase. The crystal structure of human SCF has been resolved and a potential receptor-binding site identified.
No pairwise interactions found for the domain SCF

Total Mutations Found: 5
Total Disease Mutations Found: 1
This domain occurred 1 times on human genes (3 proteins).



  HYPERPIGMENTATION, FAMILIAL PROGRESSIVE, 2


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for SCF












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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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