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  Domain Name: SEC1
Proteins involved in synaptic transmission and general secretion, Sec1 family [Intracellular trafficking and secretion]

Total Mutations Found: 28
Total Disease Mutations Found: 21
This domain occurred 7 times on human genes (12 proteins).



  ARTHROGRYPOSIS, RENAL DYSFUNCTION, AND CHOLESTASIS 1
  EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 4
  FAMILIAL HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS 5 (FHL5)
  HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS, FAMILIAL 5


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for SEC1























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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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