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  Domain Name: SNF2_N
SNF2 family N-terminal domain. This domain is found in proteins involved in a variety of processes including transcription regulation (e.g., SNF2, STH1, brahma, MOT1), DNA repair (e.g. ERCC6, RAD16, RAD5), DNA recombination (e.g. RAD54), and chromatin unwinding (e.g. ISWI) as well as a variety of other proteins with little functional information (e.g. lodestar, ETL1).
No pairwise interactions found for the domain SNF2_N

Total Mutations Found: 56
Total Disease Mutations Found: 24
This domain occurred 30 times on human genes (59 proteins).



  ALPHA-THALASSEMIA/MENTAL RETARDATION SYNDROME, X-LINKED
  BREAST CANCER, INVASIVE DUCTAL
  CEREBROOCULOFACIOSKELETAL SYNDROME 1
  CHARGE SYNDROME
  COCKAYNE SYNDROME B
  COLON CANCER, SOMATIC
  DE SANCTIS-CACCHIONE SYNDROME, INCLUDED
  EPILEPTIC ENCEPHALOPATHY, CHILDHOOD-ONSET
  LYMPHOMA, NON-HODGKIN, SOMATIC
  MENTAL RETARDATION, AUTOSOMAL DOMINANT 16
  NICOLAIDES-BARAITSER SYNDROME
  SCHIMKE IMMUNOOSSEOUS DYSPLASIA


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for SNF2_N


















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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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