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  Domain Name: SPRY
Domain in SPla and the RYanodine Receptor. Domain of unknown function. Distant homologues are domains in butyrophilin/marenostrin/pyrin homologues.
No pairwise interactions found for the domain SPRY

Total Mutations Found: 47
Total Disease Mutations Found: 9
This domain occurred 95 times on human genes (165 proteins).



  FAMILIAL MEDITERRANEAN FEVER
  FAMILIAL MEDITERRANEAN FEVER, AUTOSOMAL DOMINANT
  OPITZ SYNDROME, X-LINKED


Tips:
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 The histograms below the weblogo indicate mutations found on the domain. Red is for disease (OMIM) and blue is for SNPs.

 Functional Features are displayed as orange boxes under the histograms. You can choose which features are displayed in the box below.



Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for SPRY



















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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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