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  Domain Name: Synuclein
Synuclein. There are three types of synucleins in humans, these are called alpha, beta and gamma. Alpha synuclein has been found mutated in families with autosomal dominant Parkinson's disease. A peptide of alpha synuclein has also been found in amyloid plaques in Alzheimer's patients.
No pairwise interactions found for the domain Synuclein

Total Mutations Found: 6
Total Disease Mutations Found: 3
This domain occurred 3 times on human genes (7 proteins).



  DEMENTIA, LEWY BODY
  PARKINSON DISEASE 1, AUTOSOMAL DOMINANT


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for Synuclein








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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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