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  Domain Name: Thiol-ester_cl
Alpha-macro-globulin thiol-ester bond-forming region. This short highly conserved region of proteinase-binding alpha-macro-globulins contains the cysteine and a glutamine of a thiol-ester bond that is cleaved at the moment of proteinase binding, and mediates the covalent binding of the alpha-macro-globulin to the proteinase. The GCGEQ motif is highly conserved.
No pairwise interactions found for the domain Thiol-ester_cl

Total Mutations Found: 0
Total Disease Mutations Found: 0
This domain occurred 10 times on human genes (20 proteins).




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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for Thiol-ester_cl





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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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