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  Domain Name: WD40
WD40 repeats. Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.

Total Mutations Found: 89
Total Disease Mutations Found: 29
This domain occurred 206 times on human genes (391 proteins).



  ACHALASIA-ADDISONIANISM-ALACRIMA SYNDROME
  ASPHYXIATING THORACIC DYSTROPHY 2
  CHARCOT-MARIE-TOOTH DISEASE, DOMINANT INTERMEDIATE F
  COCKAYNE SYNDROME A
  CRANIOECTODERMAL DYSPLASIA 1
  DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 3
  IMMUNODEFICIENCY 8
  JOUBERT SYNDROME 3
  LISSENCEPHALY 1
  PEROXISOME BIOGENESIS DISORDER 9B
  RECLASSIFIED - VARIANT OF UNKNOWN SIGNIFICANCE
  RHIZOMELIC CHONDRODYSPLASIA PUNCTATA, TYPE 1
  SHORT STATURE, ONYCHODYSPLASIA, FACIAL DYSMORPHISM, AND HYPOTRICHOSIS
  SUBCORTICAL LAMINAR HETEROTOPIA
  XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP E, DDB-NEGATIVE FORM


Tips:
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 Functional Features are displayed as orange boxes under the histograms. You can choose which features are displayed in the box below.



Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for WD40








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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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