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  Domain Name: ZnF_GATA
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
No pairwise interactions are available for this conserved domain.

Total Mutations Found: 33
Total Disease Mutations Found: 33
This domain occurred 10 times on human genes (22 proteins).



  ATRIAL SEPTAL DEFECT 2
  DEFICIENCY
  DENDRITIC CELL, MONOCYTE, B LYMPHOCYTE, AND NATURAL KILLER LYMPHOCYTE
  HYPOPARATHYROIDISM, SENSORINEURAL DEAFNESS, AND RENAL DYSPLASIA SYNDROME
  LYMPHEDEMA, PRIMARY, WITH MYELODYSPLASIA
  MYELODYSPLASTIC SYNDROME, SUSCEPTIBIL
  PANCREATIC AGENESIS AND CONGENITAL CARDIAC DEFECTS
  PERSISTENT TRUNCUS ARTERIOSUS
  TESTICULAR ANOMALIES WITH OR WITHOUT CONGENITAL HEART DISEASE (1 FAMILY)
  THROMBOCYTOPENIA WITH BETA-THALASSEMIA, X-LINKED
  THROMBOCYTOPENIA, X-LINKED, WITH DYSERYTHROPOIETIC ANEMIA
  THROMBOCYTOPENIA, X-LINKED, WITHOUT DYSERYTHROPOIETIC ANEMIA
  TRICHORHINOPHALANGEAL SYNDROME, TYPE I
  TRICHORHINOPHALANGEAL SYNDROME, TYPE III
  VENTRICULAR SEPTAL DEFECT 1


Tips:
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 The histograms below the weblogo indicate mutations found on the domain. Red is for disease (OMIM) and blue is for SNPs.

 Functional Features are displayed as orange boxes under the histograms. You can choose which features are displayed in the box below.



Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


Feature Name:Total Found:
zinc binding site
DNA-binding region









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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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