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  Domain Name: dNK
Deoxynucleoside kinase. This family consists of various deoxynucleoside kinases cytidine EC:2.7.1.74, guanosine EC:2.7.1.113, adenosine EC:2.7.1.76 and thymidine kinase EC:2.7.1.21 (which also phosphorylates deoxyuridine and deoxycytosine.) These enzymes catalyze the production of deoxynucleotide 5'-monophosphate from a deoxynucleoside. Using ATP and yielding ADP in the process.
No pairwise interactions found for the domain dNK

Total Mutations Found: 16
Total Disease Mutations Found: 16
This domain occurred 4 times on human genes (11 proteins).



  LEIGH SYNDROME DUE TO MITOCHONDRIAL COMPLEX I DEFICIENCY
  MITOCHONDRIAL DNA DEPLETION SYNDROME 2 (MYOPATHIC TYPE)
  MITOCHONDRIAL DNA DEPLETION SYNDROME 3 (HEPATOCEREBRAL TYPE)


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for dNK







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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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