Results for the protein: P42166

Results for the Protein: P42166

1174689

7112

TMPO

NCBI, UniProt

LAP2A_HUMAN RecName: Full=Lamina-associated polypeptide 2, isoform alpha; AltName: Full=Thymopoietin isoform alpha; Short=TP alpha; AltName: Full=Thymopoietin-related peptide isoform alpha; Short=TPRP isoform alpha; Contains: RecName: Full=Thymopoietin; Short=TP; AltName: Full=Splenin; Contains: RecName: Full=Thymopentin; AltName: Full=TP5

Known Diseases associated with this Protein:
CARDIOMYOPATHY, DILATED 1T (CMD1T)
CARDIOMYOPATHY, DILATED, 1T

2

8

1

4

5

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: Thymopoietin - pfam08198 LEM - smart00540 LAP2alpha - pfam11560	Swiss-Prot Protein: P42166 Identical to: NP_003267 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
LEM	smart00540	2.8e-20	110	153
LAP2alpha	pfam11560	2.5e-197	461	694

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs114939776	Polymorphism	p.ALA309PRO	N/A
Swiss-Prot	VAR_049778	Disease	p.ARG690CYS	Cardiomyopathy, dilated 1T (CMD1T)
dbSNP	rs17459334	Polymorphism	p.GLN599GLU	N/A
Swiss-Prot	VAR_049773	Polymorphism	p.LEU238ARG	N/A
dbSNP	rs35761089	Polymorphism	p.LYS478ASN	N/A
Swiss-Prot	VAR_049776	Polymorphism	p.LYS416GLU	N/A
Swiss-Prot	VAR_049774	Polymorphism	p.SER293ALA	N/A
dbSNP	rs80325832	Polymorphism	p.SER491ALA	N/A
Swiss-Prot	VAR_049775	Polymorphism	p.THR317SER	N/A
OMIM	188380.0001	Disease	p.ARG690CYS	CARDIOMYOPATHY, DILATED, 1T

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258