Results for the protein: Q9NR80

Results for the Protein: Q9NR80

229463003

50649

ARHGEF4

NCBI, UniProt

ARHG4_HUMAN RecName: Full=Rho guanine nucleotide exchange factor 4; AltName: Full=APC-stimulated guanine nucleotide exchange factor 1; Short=Asef; Short=Asef1

			0 4 0 1 3

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

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To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: SH3 - smart00326 SH3_2 - pfam07653 SH3 - cd00174 SH3_1 - pfam00018 RhoGEF - cd00160 RhoGEF - smart00325 RhoGEF - pfam00621 PH_Collybistin_ASEF - cd01224 PH_SOS - cd01261 PH - smart00233 PH - pfam00169 PH-like - cd00900 PH - cd00821	Swiss-Prot Protein: Q9NR80 Identical to: NP_056135 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
RhoGEF	cd00160	3.2e-58	285	466
PH_Collybistin_ASEF	cd01224	2.9e-54	499	607
PH_SOS	cd01261	0.00078	499	604
PH	cd00821	4.8e-14	502	604
PH-like	cd00900	3.3e-11	502	604
SH3_1	pfam00018	3.9e-10	200	245
RhoGEF	pfam00621	6.1e-60	289	467
PH	pfam00169	2.5e-09	500	606
SH3	smart00326	3.9e-17	195	251
SH3_2	pfam07653	1.7e-05	198	250
RhoGEF	smart00325	4.6e-57	288	467
PH	smart00233	6.5e-12	500	606

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_057187	Polymorphism	p.ASP33HIS	N/A
Swiss-Prot	VAR_035970	Polymorphism	p.LYS100ARG	N/A
Swiss-Prot	VAR_035971	Polymorphism	p.THR441ARG	N/A
dbSNP	rs61750360	Polymorphism	p.VAL85ILE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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