Results for the protein: NP

Results for the Protein: NP_001159451

260166694

51196

PLCE1

NCBI

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform 2 [Homo sapiens]

Known Diseases associated with this Protein:
NEPHROTIC SYNDROME, TYPE 3

7

6

7

6

0

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PI-PLCc	cd00137	2.4e-32	1083	1525
PI-PLCc_eukaryota	cd08558	1.8e-178	1083	1525
PI-PLCc_beta	cd08591	1.5e-75	1083	1525
PI-PLCc_zeta	cd08595	7.7e-55	1083	1525
PI-PLCc_epsilon	cd08596		1083	1525
PI-PLCc_plant	cd08599	4.6e-27	1083	1525
PI-PLCc_gamma	cd08592	3.8e-12	1083	1812
PI-PLC1c_yeast	cd08598	5.9e-76	1083	1525
PI-PLCc_beta1	cd08623	8e-55	1083	1525
PI-PLCc_beta3	cd08625	3.5e-53	1083	1525
PI-PLCc_beta4	cd08626	1.6e-57	1083	1525
PI-PLCc_delta1	cd08629	1.8e-52	1083	1525
PI-PLCc_delta3	cd08630	8.6e-55	1083	1525
PI-PLCc_delta4	cd08631	2e-54	1083	1525
PI-PLCc_eta1	cd08632	4.9e-59	1083	1525
PI-PLCc_gamma2	cd08628	6.3e-09	1083	1525
PI-PLCc_eta2	cd08633	9.5e-48	1083	1525
PI-PLCc_beta2	cd08624	5.8e-57	1083	1525
PI-PLCc_gamma1	cd08627	2e-06	1084	1852
PI-PLCc_PRIP_metazoa	cd08597	2.7e-60	1089	1525
PI-PLCc_delta	cd08593	1.2e-82	1089	1525
PI-PLCc_eta	cd08594	1.1e-61	1089	1525
PI-PLCc_GDPD_SF	cd08555	2.7e-13	1096	1345
C2_PLC_like	cd00275	6.6e-41	1560	1680
C2	cd00030	1.5e-05	1563	1663
PLC_epsilon_RA	cd01780	6.5e-75	1829	1928
RA	cd01768	2e-25	1830	1928
RasGEF	pfam00617	3.1e-18	220	458
PI-PLC-X	pfam00388	2.7e-88	1086	1233
PI-PLC-Y	pfam00387	6.9e-42	1426	1538
C2	pfam00168	4.3e-09	1563	1645
RA	pfam00788	2.2e-31	1830	1930
RasGEF	smart00147	5.5e-08	220	523
PLCXc	smart00148	1.5e-75	1084	1222
PLCYc	smart00149	1.1e-45	1425	1537
C2	smart00239	2.4e-12	1562	1660
RA	smart00314	3.5e-05	1827	1929

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs17417407	Polymorphism	p.ARG240LEU	N/A
dbSNP	rs2274224	Polymorphism	p.ARG1267PRO	N/A
dbSNP	rs2274223	Polymorphism	p.HIS1619ARG	N/A
dbSNP	rs58539480	Polymorphism	p.PRO1582LEU	N/A
dbSNP	rs17508082	Polymorphism	p.SER161THR	N/A
dbSNP	rs3765524	Polymorphism	p.THR1469ILE	N/A
OMIM	608414.0008	Disease	p.ARG1842TER	NEPHROTIC SYNDROME, TYPE 3
OMIM	608414.0002	Disease	p.ARG185TER	NEPHROTIC SYNDROME, TYPE 3
OMIM	608414.0003	Disease	p.ARG808TER	NEPHROTIC SYNDROME, TYPE 3
OMIM	608414.0010	Disease	p.ARG938TER	NEPHROTIC SYNDROME, TYPE 3
OMIM	608414.0005	Disease	p.GLN1308TER	NEPHROTIC SYNDROME, TYPE 3
OMIM	608414.0006	Disease	p.GLN1546TER	NEPHROTIC SYNDROME, TYPE 3
OMIM	608414.0007	Disease	p.SER1176LEU	NEPHROTIC SYNDROME, TYPE 3

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258