Results for the protein: NP

Results for the Protein: NP_001180449

302058252

8437

RASAL1

NCBI

rasGAP-activating-like protein 1 isoform 1 [Homo sapiens]

			0 3 0 3 0

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

RefSeq Protein: NP_001180449

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
C2B_Synaptotagmin-1	cd08402	0.00029	1	108
C2B_Ferlin	cd04011	0.00054	2	112
C2A_Synaptotagmin-1-	cd08385	4e-05	2	109
C2B_Synaptotagmin-7	cd08405	2.7e-07	4	108
C2B_Munc13	cd04027	3.6e-05	5	124
C2C_MCTP_PRT	cd08377	2.5e-06	5	127
C2_fungal_Inn1p-like	cd08681	0.0002	5	126
C2_PKC_epsilon	cd04014	5.8e-07	6	116
C2A_MCTP_PRT_plant	cd04022	0.00023	6	128
C2A_MCTP_PRT	cd04042	4.5e-06	6	128
C2A_Rasal1_RasA4	cd04054	7.1e-78	6	126
C2_Smurf-like	cd08382	4.6e-05	6	125
C2A_RasGAP	cd08383	4e-55	6	126
C2A_RasA2_RasA3	cd08401	6.6e-23	6	126
C2	cd00030	4e-24	7	107
C2A_Synaptotagmin-li	cd04024	2e-06	7	126
C2_ArfGAP	cd04038	1.1e-06	7	130
C2D_Tricalbin-like	cd04040	1.3e-07	7	123
C2B_MCTP_PRT	cd08376	7e-05	7	142
C2_KIAA0528-like	cd08688	6.5e-06	7	108
C2_Munc13_fungal	cd04043	0.0001	9	129
C2_Perforin	cd04032	0.00071	114	224
C2A_Synaptotagmin-7	cd08386	0.00022	116	235
C2A_Synaptotagmin-8	cd08387	4.9e-06	116	236
C2_PKC_alpha_gamma	cd04026	5.7e-11	117	248
C2A_SLP	cd08521	0.00098	118	233
C2B_Rabphilin_Doc2	cd08384	1.2e-05	119	233
C2B_Munc13-like	cd04009	3.5e-06	121	235
C2A_RIM1alpha	cd04031	3.2e-06	121	234
C2A_Rabphilin_Doc2	cd04035	8.7e-08	124	234
C2B_RasA1_RasA4	cd04025	1.4e-90	134	255
C2_NEDD4_NEDD4L	cd04033	8.8e-06	134	257
C2E_Ferlin	cd04037	5.7e-06	134	250
C2A_Rasal1_RasA4	cd04054	1.2e-05	134	252
C2	cd00030	1.9e-26	135	233
C2D_Ferlin	cd04017	4.5e-11	135	260
C2A_Synaptotagmin-li	cd04024	1.6e-09	135	256
C2D_Tricalbin-like	cd04040	6.5e-08	135	253
C2A_fungal	cd04041	3.3e-05	135	236
C2A_C2C_Synaptotagmi	cd08391	1.2e-06	135	258
C2B_RasGAP	cd08675	3.6e-51	135	250
C2_Rab11-FIP_classI	cd08682	6.8e-06	137	255
C2B_MCTP_PRT_plant	cd08378	0.00049	139	246
C2B_Copine	cd04047	0.00014	140	226
RasGAP_CLA2_BUD2	cd05137	1.7e-16	211	601
RasGAP	cd04519	1.2e-93	265	598
RasGAP_GAP1_like	cd05128	3.2e-218	265	598
RasGAP_RASA3	cd05134	1.9e-45	265	599
RasGAP_RASAL	cd05135	3.5e-282	265	598
RasGAP_Neurofibromin	cd05130	1.2e-07	265	608
RasGAP_RASA2	cd05394	6.6e-29	265	599
RasGAP_RASA4	cd05395	8.1e-161	265	700
RasGAP_p120GAP	cd05391	3.9e-12	267	606
RasGAP_Neurofibromin	cd05392	1.4e-17	287	609
RasGAP_DAB2IP	cd05136	1.2e-12	292	580
RasGAP_IQGAP_like	cd05127	9.4e-06	321	600
RasGAP_GAPA	cd05132	1.6e-07	324	597
PH	cd00821	4.9e-13	570	672
PH-like	cd00900	1.7e-05	570	672
PH_GAP1-like	cd01244	1.2e-24	570	672
C2	pfam00168	3.6e-24	7	88
C2	pfam00168	5.6e-27	135	216
RasGAP	pfam00616	1.8e-66	322	512
PH	pfam00169	6.6e-13	568	674
BTK	pfam00779	3.7e-13	681	711
C2	smart00239	6.2e-20	6	103
C2	smart00239	7.9e-24	134	231
RasGAP	smart00323	5.5e-149	242	606
PH	smart00233	9.3e-15	568	674
BTK	smart00107	0.00018	676	711

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs1284879	Polymorphism	p.ARG321HIS	N/A
dbSNP	rs34598602	Polymorphism	p.THR58MET	N/A
dbSNP	rs7960087	Polymorphism	p.VAL11LEU	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258