Home News About DMDM Database Statistics Research Publications Contact  

Results for the Protein: NP_001186491
313760592

85 kDa calcium-independent phospholipase A2 isoform b [Homo sapiens]

Known Diseases associated with this Protein:
  KARAK SYNDROME
  NEURODEGENERATION WITH BRAIN IRON ACCUMULATION 2A
  NEURODEGENERATION WITH BRAIN IRON ACCUMULATION 2B
  PARKINSON DISEASE 14
12
1
12
1
0
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

ANK - cd00204
Arp - COG0666
ANK - smart00248
Ank - pfam00023
COG3621 - COG3621
Pat_PNPLA8 - cd07211
Pat17_PNPLA8_PNPLA9_ - cd07216
Pat17_PNPLA8_PNPLA9_ - cd07217
Pat17_PNPLA8_PNPLA9_ - cd07215
Pat_PNPLA9 - cd07212
Pat17_PNPLA8_PNPLA9_ - cd07199
Pat_ExoU_VipD_like - cd07207
Pat17_PNPLA8_PNPLA9_ - cd07213
Patatin - pfam01734
Pat17_isozyme_like - cd07214




Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
ArpCOG06665.1e-15150390
ANKcd002041.6e-30280403
Pat_PNPLA8cd072112.3e-15417738
Pat17_PNPLA8_PNPLA9_cd072162.7e-11424736
Pat17_PNPLA8_PNPLA9_cd072151.5e-11425749
Pat17_PNPLA8_PNPLA9_cd072172.2e-08425744
Pat17_PNPLA8_PNPLA9_cd071992.8e-76426736
Pat_ExoU_VipD_likecd072070.0002426616
Pat_PNPLA9cd072122e-232426739
Pat17_PNPLA8_PNPLA9_cd072133.6e-10427732
Pat17_isozyme_likecd072140.00089427734
Ankpfam000237.2e-05219251
Ankpfam000237.1e-07316348
Ankpfam000234.3e-08349381
COG3621COG36212.9e-06416752
Patatinpfam017342.2e-24427611
ANKsmart002480.00018219248
ANKsmart002482.1e-05316345
ANKsmart002482.5e-06349378

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
dbSNPrs11570605 Polymorphismp.VAL58ILEN/A
OMIM603604.0008 Diseasep.ALA80THRNEURODEGENERATION WITH BRAIN IRON ACCUMULATION 2B
OMIM603604.0011 Diseasep.ARG581GLNPARKINSON DISEASE 14
OMIM603604.0009 Diseasep.ARG687GLNPARKINSON DISEASE 14
OMIM603604.0015 Diseasep.ARG37TERNEURODEGENERATION WITH BRAIN IRON ACCUMULATION 2A
OMIM603604.0005 Diseasep.ARG578TRPKARAK SYNDROME
OMIM603604.0010 Diseasep.ARG693TRPPARKINSON DISEASE 14
OMIM603604.0016 Diseasep.ASP331TYRPARKINSON DISEASE 14
OMIM603604.0012 Diseasep.GLN398TERPARKINSON DISEASE 14
OMIM603604.0002 Diseasep.LYS491THRNEURODEGENERATION WITH BRAIN IRON ACCUMULATION 2B
OMIM603604.0013 Diseasep.PHE72LEUPARKINSON DISEASE 14
OMIM603604.0001 603604.0006 Diseasep.TYR736TERNEURODEGENERATION WITH BRAIN IRON ACCUMULATION 2A
OMIM603604.0003 Diseasep.VAL310GLUNEURODEGENERATION WITH BRAIN IRON ACCUMULATION 2A



   |   1000 Hilltop Circle, Baltimore, MD 21250   |   Department of Biological Sciences   |   Phone: 410-455-2258