Results for the protein: P49736

Results for the Protein: P49736

41019490

4171

MCM2

NCBI, UniProt

MCM2_HUMAN RecName: Full=DNA replication licensing factor MCM2; AltName: Full=Minichromosome maintenance protein 2 homolog; AltName: Full=Nuclear protein BM28

			0 7 0 2 5

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Default View: MCM2_N - pfam12619 MCM2 - COG1241 MCM - smart00350 MCM - pfam00493 COG0714 - COG0714 Mg_chelatase - pfam01078 AAA_5 - pfam07728 AAA_3 - pfam07726	Swiss-Prot Protein: P49736 Identical to: NP_004517 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
COG0714	COG0714	0.0003	460	810
MCM	pfam00493	2.2e-213	460	803
Mg_chelatase	pfam01078	4.9e-05	484	675
MCM2_N	pfam12619	9.4e-44	1	182
MCM	smart00350		290	803
AAA_3	pfam07726	0.00087	518	659
AAA_5	pfam07728	0.00017	518	657

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_016137	Polymorphism	p.ALA396THR	N/A
Swiss-Prot	VAR_016139	Polymorphism	p.ALA727THR	N/A
dbSNP	rs3087452	Polymorphism	p.ASP68GLU	N/A
Swiss-Prot	VAR_033298	Polymorphism	p.GLU166GLN	N/A
Swiss-Prot	VAR_033299	Polymorphism	p.GLY501ARG	N/A
Swiss-Prot	VAR_021112	Polymorphism	p.LEU135PHE	N/A
dbSNP	rs2307311	Polymorphism	p.VAL667MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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