Results for the protein: Q6P3R8

Results for the Protein: Q6P3R8

74758252

341676

NEK5

NCBI, UniProt

NEK5_HUMAN RecName: Full=Serine/threonine-protein kinase Nek5; AltName: Full=Never in mitosis A-related kinase 5; Short=NimA-related protein kinase 5

			0 5 0 2 3

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: Q6P3R8

Identical to: NP_954983

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PTKc_EphR	cd05033	2.2e-08	1	263
PTKc_Csk_like	cd05039	1.3e-08	1	260
PTKc_Ror	cd05048	5.1e-08	1	262
PTKc_Trk	cd05049	2.9e-09	1	261
PTKc_Abl	cd05052	3e-18	1	263
PTKc_EGFR_like	cd05057	3.2e-06	1	270
PTKc_Tec_like	cd05059	6e-11	1	236
PTKc_InsR	cd05061	1.5e-07	1	273
PTKc_IGF-1R	cd05062	2.4e-07	1	255
PTKc_EphR_A10	cd05064	2.2e-06	1	258
PTKc_EphR_B	cd05065	5.4e-08	1	263
PTKc_EphR_A	cd05066	1.6e-11	1	263
PTKc_Lck_Blk	cd05067	6.2e-08	1	262
PTKc_Frk_like	cd05068	1.4e-18	1	262
PTKc_Yes	cd05069	5.7e-10	1	262
PTKc_Fyn_Yrk	cd05070	1.2e-08	1	262
PTKc_Src	cd05071	1.1e-08	1	264
PTKc_Lyn	cd05072	2.9e-10	1	257
PTKc_Hck	cd05073	7.4e-10	1	257
PTKc_Jak1_rpt2	cd05079	1e-05	1	263
PTKc_Csk	cd05082	1.2e-07	1	262
PTKc_Chk	cd05083	2e-14	1	260
PTKc_Ror1	cd05090	3.7e-06	1	262
PTKc_Ror2	cd05091	7.1e-05	1	262
PTKc_TrkA	cd05092	4.7e-07	1	256
PTKc_TrkB	cd05093	1.3e-07	1	268
PTKc_TrkC	cd05094	8e-07	1	307
PTKc_DDR2	cd05095	0.00034	1	260
PTKc_DDR_like	cd05097	0.00045	1	261
PTKc_FGFR1	cd05098	2.6e-05	1	270
PTKc_FGFR4	cd05099	3.3e-07	1	279
PTKc_FGFR3	cd05100	1.6e-05	1	298
PTKc_FGFR2	cd05101	5.4e-07	1	270
PTKc_VEGFR3	cd05102	4.7e-05	1	266
PTKc_VEGFR2	cd05103	0.00034	1	266
PTKc_Tie2	cd05088	1.9e-07	1	282
PTK_HER3	cd05111	2.5e-06	1	273
PTKc_Btk_Bmx	cd05113	1.3e-10	1	258
STKc_ROCK	cd05596	4e-06	1	315
STKc_ROCK2	cd05621	6.2e-07	1	322
STKc_ROCK1	cd05622	6.6e-06	1	311
STKc_SLK_like	cd06611	2.9e-16	1	274
STKc_MAP4K3_like	cd06613	7.5e-36	1	258
PKc_MKK7	cd06618	3.8e-11	1	274
STKc_ASK	cd06624	1.5e-33	1	259
STKc_TAO1	cd06635	8.4e-09	1	307
STKc_myosinIIIA	cd06638	4.6e-11	1	259
STKc_myosinIIIB	cd06639	9.6e-11	1	260
STKc_MAP4K4_6	cd06636	5.5e-14	1	259
STKc_MAP4K3	cd06645	3e-26	1	258
STKc_MAP4K5	cd06646	3.8e-22	1	258
STKc_PAK_I	cd06647	3.4e-22	1	279
STKc_PAK1	cd06654	2e-10	1	281
STKc_PAK2	cd06655	1.1e-14	1	283
STKc_PAK3	cd06656	1.6e-11	1	283
STKc_PAK4	cd06657	7.5e-10	1	277
STKc_PAK5	cd06658	2e-08	1	275
STKc_PAK6	cd06659	2.5e-11	1	282
STKc_STK10_LOK	cd06644	2e-21	1	279
STKc_PCTAIRE_like	cd07844	7.1e-20	1	302
STKc_JNK	cd07850	1.1e-08	1	339
STKc_MAPK15	cd07852	2e-11	1	279
STKc_TEY_MAPK_plant	cd07858	1.2e-10	1	305
STKc_CDK9	cd07865	5.2e-12	1	259
STKc_BUR1	cd07866	2.4e-12	1	259
STKc_CDC2L6	cd07867	8.9e-06	1	306
STKc_CDK8	cd07868	3.9e-05	1	314
STKc_PFTAIRE1	cd07869	4.5e-07	1	269
STKc_PFTAIRE2	cd07870	9.3e-09	1	281
STKc_CDK12	cd07864	1.5e-15	1	259
STKc_PCTAIRE3	cd07871	1.4e-09	1	281
STKc_PCTAIRE2	cd07872	5e-09	1	279
STKc_JNK3	cd07874	5e-07	1	341
STKc_JNK1	cd07875	1.6e-05	1	368
STKc_JNK2	cd07876	9e-06	1	366
STKc_p38gamma_MAPK12	cd07880	3.1e-07	1	333
STKc_PCTAIRE1	cd07873	2.5e-08	1	270
STKc_CDK10	cd07845	1.8e-11	1	271
STKc_Nek6_Nek7	cd08224	4.4e-62	1	262
STKc_Nek7	cd08229	7.9e-49	1	259
STKc_Nek6	cd08228	4.6e-51	1	262
PTKc_ALK_LTK	cd05036	1.7e-12	2	261
PTKc_Musk	cd05050	3.8e-08	2	256
PTKc_DDR	cd05051	0.00017	2	261
PTKc_FGFR	cd05053	1.4e-07	2	264
PTKc_FAK	cd05056	1.6e-09	2	267
PTKc_EphR_A2	cd05063	1.8e-07	2	263
PTKc_Src_like	cd05034	1.3e-11	2	262
PTKc_EGFR	cd05108	7.6e-06	2	312
PTKc_HER2	cd05109	3.1e-06	2	273
PTKc_HER4	cd05110	5.8e-05	2	267
PTKc_Tec_Rlk	cd05114	3.5e-12	2	258
PTKc_Itk	cd05112	4.6e-12	2	258
STKc_phototropin_lik	cd05574	8.9e-12	2	280
STKc_PKA	cd05580	5.8e-18	2	279
STKc_PDK1	cd05581	1.5e-28	2	259
STKc_DMPK_like	cd05597	3.7e-09	2	319
STKc_LATS	cd05598	1.6e-08	2	316
STKc_NDR_like	cd05599	7.2e-09	2	307
STKc_Sid2p_Dbf2p	cd05600	5.3e-08	2	327
STKc_CRIK	cd05601	2e-11	2	316
STKc_ROCK_NDR_like	cd05573	2.4e-14	2	309
STKc_MAST	cd05609	3.6e-10	2	317
STKc_PRKX_like	cd05612	4.2e-11	2	302
STKc_MRCK_alpha	cd05623	4.6e-08	2	310
STKc_MRCK_beta	cd05624	7.3e-09	2	307
STKc_LATS2	cd05626	3.8e-05	2	330
STKc_NDR2	cd05627	1.4e-06	2	364
STKc_NDR1	cd05628	2.8e-08	2	312
STKc_LATS1	cd05625	6.2e-06	2	324
STKc_NDR_like_fungal	cd05629	5.2e-07	2	335
PKc_MAPKK	cd06605	6.4e-18	2	261
STKc_TAO	cd06607	1.1e-10	2	307
STKc_myosinIII_like	cd06608	3.6e-16	2	259
STKc_MST3_like	cd06609	3.3e-23	2	279
STKc_OSR1_SPAK	cd06610	1.5e-24	2	259
STKc_MST1_2	cd06612	1.7e-26	2	259
STKc_PAK	cd06614	6.7e-25	2	271
PKc_MKK3_6	cd06617	9.4e-13	2	277
PKc_MKK5	cd06619	6.1e-07	2	289
PKc_MEK	cd06615	5.2e-11	2	267
PKc_MAPKK_Byr1_like	cd06620	1.4e-09	2	310
PKc_MAPKK_Pek1_like	cd06621	1.9e-14	2	266
PKc_MAPKK_PBS2_like	cd06622	1.6e-10	2	314
PKc_MAPKK_plant_like	cd06623	6.9e-29	2	261
STKc_TAO3	cd06633	5e-07	2	307
STKc_TAO2	cd06634	1e-11	2	308
STKc_MST4	cd06640	4.7e-21	2	280
STKc_MST3	cd06641	3.2e-18	2	279
STKc_STK25-YSK1	cd06642	1.1e-16	2	279
STKc_SLK	cd06643	3.9e-17	2	277
STKc_PAK_II	cd06648	1.3e-14	2	272
PKc_MEK2	cd06649	5.1e-08	2	323
PKc_MEK1	cd06650	4.9e-07	2	327
STKc_MEKK2	cd06652	9.5e-12	2	260
STKc_MEKK3_like_1	cd06653	1.6e-15	2	259
STKc_NAK1_like	cd06917	3.4e-16	2	267
STKc_CDKL	cd07833	8.7e-13	2	259
STKc_CdkB_plant	cd07837	4.4e-14	2	260
STKc_CDC2L1	cd07843	1.3e-10	2	259
STKc_CDKL2_3	cd07846	2e-11	2	259
STKc_CDKL1_4	cd07847	1.6e-25	2	302
STKc_CDKL5	cd07848	2.6e-07	2	277
STKc_ERK1_2_like	cd07849	1.2e-09	2	294
STKc_p38	cd07851	1.1e-11	2	306
STKc_ERK5	cd07855	3.2e-10	2	279
STKc_Sty1_Hog1	cd07856	4.5e-08	2	283
STKc_CDK6	cd07862	1.1e-07	2	284
STKc_p38alpha_MAPK14	cd07877	4.2e-06	2	319
STKc_p38beta_MAPK11	cd07878	7.1e-06	2	323
STKc_p38delta_MAPK13	cd07879	0.00029	2	301
SPS1	COG0515	5.7e-66	2	454
PTKc_Jak_rpt2	cd05038	1.1e-10	3	263
PTKc_RET	cd05045	1.5e-06	3	266
PTKc_PDGFR	cd05055	5.7e-06	3	263
PKc_STE	cd05122	4.8e-57	3	258
STKc_Yank1	cd05578	8.5e-25	3	259
STKc_MSK_N	cd05583	5.5e-15	3	278
STKc_cPKC	cd05587	6.7e-25	3	308
STKc_GRK4_like	cd05605	1.4e-13	3	280
STKc_MSK2_N	cd05614	4.7e-11	3	325
STKc_cPKC_alpha	cd05615	7.6e-12	3	313
STKc_cPKC_beta	cd05616	6.1e-10	3	329
STKc_MSK1_N	cd05613	5e-10	3	278
STKc_GRK6	cd05630	5.1e-08	3	280
STKc_GRK4	cd05631	6.3e-08	3	280
STKc_GRK5	cd05632	3.5e-09	3	280
STKc_MAPKKK	cd06606	1e-53	3	259
STKc_Cdc7_like	cd06627	3.8e-31	3	259
STKc_MAPKKK_Byr2_lik	cd06628	3.1e-39	3	259
STKc_YSK4	cd06631	8.2e-14	3	259
STKc_MEKK3	cd06651	2.3e-21	3	261
STKc_CCRK	cd07832	1.6e-14	3	260
STKc_MAPK	cd07834	1.7e-12	3	284
STKc_Pho85	cd07836	7.5e-21	3	302
STKc_CDK7	cd07841	1.1e-16	3	264
STKc_CDK8_like	cd07842	1e-11	3	259
STKc_CDK5	cd07839	2.7e-12	3	259
STKc_NLK	cd07853	5.9e-09	3	330
STKc_MAPK4_6	cd07854	3.4e-10	3	292
STKc_MPK1	cd07857	3.3e-09	3	284
STKc_TDY_MAPK_plant	cd07859	2.1e-08	3	306
STKc_CDK2_3	cd07860	1.9e-19	3	259
STKc_CDK1_euk	cd07861	1.3e-19	3	302
STKc_CDK4	cd07863	1.7e-09	3	259
STKc_Nek	cd08215	1.8e-169	3	259
STKc_Nek2	cd08217	5.8e-97	3	259
STKc_Nek1	cd08218	5e-154	3	259
STKc_Nek3	cd08219	1.2e-121	3	259
STKc_Nek8	cd08220	1e-103	3	259
STKc_Nek9	cd08221	1.1e-101	3	259
STKc_Nek11	cd08222	3.8e-74	3	259
STKc_Nek4	cd08223	1.1e-93	3	259
STKc_Nek5	cd08225	1.9e-216	3	259
STKc_Nek10	cd08528	5.5e-46	3	256
STKc_FA2-like	cd08529	5.9e-92	3	259
STKc_CNK2-like	cd08530	5.5e-82	3	259
PTKc_Axl_like	cd05035	1.1e-06	4	263
PTKc_Tyro3	cd05074	1.2e-05	4	263
PTKc_Axl	cd05075	0.00014	4	263
PTKc_Tie1	cd05089	1.1e-07	4	282
STKc_CMGC	cd05118	6.4e-19	4	259
PTKc_Srm_Brk	cd05148	2.8e-10	4	262
STKc_PKN	cd05589	1.6e-11	4	307
STKc_MAPKKK_Bck1_lik	cd06629	2.7e-14	4	259
STKc_TNIK	cd06637	2e-15	4	259
STKc_CDK_like	cd07829	1.1e-23	4	259
STKc_MAK_like	cd07830	9.3e-19	4	259
STKc_MOK	cd07831	1.2e-13	4	259
STKc_CDK1_like	cd07835	6e-20	4	295
STKc_CDK4_6_like	cd07838	3.8e-13	4	259
STKc_CDK9_like	cd07840	4.7e-18	4	259
PK_STRAD_beta	cd08226	0.00018	5	318
PK_STRAD	cd08216	3.8e-09	5	269
PK_STRAD_alpha	cd08227	1.4e-05	5	360
PTKc_Tyk2_rpt2	cd05080	4.5e-07	6	264
PTK_CCK4	cd05046	3.4e-08	7	261
PTKc_Jak2_Jak3_rpt2	cd05081	2.9e-08	7	263
STKc_RSK_N	cd05582	3.5e-22	7	302
STKc_p70S6K	cd05584	6e-22	7	336
STKc_Rim15_like	cd05611	4.3e-09	7	262
PTKc	cd00192	3.4e-34	8	258
PTK_Jak_rpt1	cd05037	3.9e-05	8	258
PTKc_Ack_like	cd05040	2.6e-09	8	260
PTKc_Aatyk	cd05042	2.6e-07	8	238
PTKc_Fes_like	cd05041	3.4e-11	8	259
PTKc_c-ros	cd05044	1.6e-08	8	256
PTKc_Tie	cd05047	3.8e-07	8	260
PTKc_Met_Ron	cd05058	2.9e-09	8	265
PTK_Jak1_rpt1	cd05077	9.6e-05	8	258
PTK_Jak2_Jak3_rpt1	cd05078	1.4e-05	8	258
PTKc_Fes	cd05084	9.2e-09	8	259
PTKc_Fer	cd05085	1.7e-08	8	259
PTKc_Aatyk2	cd05086	9.9e-06	8	259
PTKc_Syk_like	cd05060	4.1e-09	8	259
PTKc_Aatyk1_Aatyk3	cd05087	4.8e-05	8	258
PTKc_Syk	cd05116	1.7e-07	8	259
STKc_PKB	cd05571	1.5e-18	8	309
STKc_SGK	cd05575	2.1e-10	8	309
STKc_PKC	cd05570	2.1e-16	8	279
STKc_aPKC	cd05588	2.6e-10	8	313
STKc_nPKC_eta	cd05590	5.8e-18	8	317
STKc_PKB_gamma	cd05593	1.7e-10	8	316
STKc_nPKC_epsilon	cd05591	9.7e-21	8	313
STKc_PKB_alpha	cd05594	6.9e-13	8	315
STKc_nPKC_theta_delt	cd05592	4.2e-23	8	311
STKc_PKB_beta	cd05595	1.2e-09	8	314
STKc_SGK1	cd05602	1.3e-09	8	311
STKc_SGK2	cd05603	4.4e-16	8	303
STKc_SGK3	cd05604	3.6e-15	8	311
STKc_aPKC_zeta	cd05617	5.3e-09	8	313
STKc_nPKC_theta	cd05619	6.1e-12	8	311
STKc_nPKC_delta	cd05620	1.1e-06	8	328
STKc_aPKC_iota	cd05618	1.9e-08	8	313
STKc_MEKK3_like	cd06625	1.6e-30	8	259
STKc_MEKK1	cd06630	3.5e-13	8	260
STKc_MEKK1_plant	cd06632	2.3e-29	8	259
STKc_MEKK4	cd06626	2.5e-19	8	259
PTKc_Zap-70	cd05115	1.8e-07	9	262
STKc_beta_ARK	cd05606	4.7e-10	9	283
STKc_GRK3	cd05633	5.4e-08	9	274
PKc_MKK4	cd06616	5e-10	9	280
PKc	cd00180	1.8e-88	10	257
STKc_AGC	cd05123	1.8e-39	10	259
STKc_cGK_PKG	cd05572	3.9e-17	10	266
STKc_GRK	cd05577	5.2e-11	10	265
STKc_MAST_like	cd05579	2.6e-21	10	264
STKc_YPK1_like	cd05585	9.6e-13	10	306
STKc_Sck1_like	cd05586	9e-11	10	354
STKc_GRK7	cd05607	9.2e-09	10	279
STKc_GRK1	cd05608	5.9e-12	10	279
PTK_Ryk	cd05043	2.5e-05	18	239
Pkinase	pfam00069	5e-79	4	259
Pkinase_Tyr	pfam07714	3.1e-24	4	259
TyrKc	smart00219	2.5e-29	4	259
STYKc	smart00221	2.1e-84	4	259
S_TKc	smart00220	3.7e-95	14	259
KIND	smart00750	8.5e-06	94	267

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_040922	Polymorphism	p.ARG290HIS	N/A
dbSNP	rs55776590	Polymorphism	p.ASP550TYR	N/A
Swiss-Prot	VAR_040923	Polymorphism	p.CYS531ARG	N/A
dbSNP	rs56369842	Polymorphism	p.HIS233ARG	N/A
Swiss-Prot	VAR_051652	Polymorphism	p.LYS255GLN	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258