Home News About DMDM Database Statistics Research Publications Contact  

 
  Domain Name: COG1112
Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]
No pairwise interactions found for the domain COG1112

Total Mutations Found: 45
Total Disease Mutations Found: 32
This domain occurred 7 times on human genes (13 proteins).



  AMYOTROPHIC LATERAL SCLEROSIS 4, JUVENILE
  DISTAL SPINAL MUSCULAR ATROPHY, AUTOSOMAL RECESSIVE, 1
  NEURONOPATHY, DISTAL HEREDITARY MOTOR, 6 (HMN6)
  SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 1


Tips:
 If you've navigated here from a protein, hovering over a position on the weblogo will display the corresponding protein position for that domain position.

 The histograms below the weblogo indicate mutations found on the domain. Red is for disease (OMIM) and blue is for SNPs.

 Functional Features are displayed as orange boxes under the histograms. You can choose which features are displayed in the box below.



Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for COG1112

































Weblogos are Copyright (c) 2002 Regents of the University of California




Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

   |   1000 Hilltop Circle, Baltimore, MD 21250   |   Department of Biological Sciences   |   Phone: 410-455-2258