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  Domain Name: Carboxyl_trans
Carboxyl transferase domain. All of the members in this family are biotin dependent carboxylases. The carboxyl transferase domain carries out the following reaction; transcarboxylation from biotin to an acceptor molecule. There are two recognised types of carboxyl transferase. One of them uses acyl-CoA and the other uses 2-oxoacid as the acceptor molecule of carbon dioxide. All of the members in this family utilise acyl-CoA as the acceptor molecule.
No pairwise interactions found for the domain Carboxyl_trans

Total Mutations Found: 19
Total Disease Mutations Found: 16
This domain occurred 4 times on human genes (9 proteins).



  3-@METHYLCROTONYL-COA CARBOXYLASE 2 DEFICIENCY
  PROPIONIC ACIDEMIA


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for Carboxyl_trans





















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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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