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  Domain Name: Complex1_LYR
Complex 1 protein (LYR family). Proteins in this family have been identified as a component of the higher eukaryotic NADH complex. In Saccharomyces cerevisiae, the Isd11 protein has been shown to play a role in Fe/S cluster biogenesis in mitochondria. We have named this family LYR after a highly conserved tripeptide motif close to the N-terminus of these proteins.
No pairwise interactions found for the domain Complex1_LYR

Total Mutations Found: 11
Total Disease Mutations Found: 2
This domain occurred 11 times on human genes (15 proteins).



  COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 19 (1 FAMILY)
  MITOCHONDRIAL COMPLEX I DEFICIENCY


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for Complex1_LYR









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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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