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  Domain Name: Na_trans_assoc
Sodium ion transport-associated. Members of this family contain a region found exclusively in eukaryotic sodium channels or their subunits, many of which are voltage-gated. Members very often also contain between one and four copies of pfam00520 and, less often, one copy of pfam00612.
No pairwise interactions found for the domain Na_trans_assoc

Total Mutations Found: 58
Total Disease Mutations Found: 10
This domain occurred 10 times on human genes (30 proteins).



  ATRIAL FIBRILLATION, FAMILIAL, 10, INCLUDED
  BRUGADA SYNDROME 1
  EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 11
  GENERALIZED EPILEPSY WITH FEBRILE SEIZURES PLUS, TYPE 2
  LONG QT SYNDROME 3
  LONG QT SYNDROME 3, ACQUIRED, SUSCEPTIBILITY TO, INCLUDED
  PAROXYSMAL EXTREME PAIN DISORDER
  SEIZURES, BENIGN FAMILIAL INFANTILE, 3


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for Na_trans_assoc
















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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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